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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a59d970d7d2da43b5e77eefba0e7b263bcb6445289a431194cc5d25d5007d8b1' 
  AND token = 'YWPnbfKnG/apoKql72D73IZurbGqJxr10J6oA9bMd04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}