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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '604c2afd485fa654b21f31925b214ddadacab1d19cdf50c8b3f45f5d2c4d3a47' 
  AND token = '4kfUGGv8WN+sfJUMhnsoZpLtrFWSRqXwdDYzcc95JeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}