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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e161c6d48cd5499c8a8af0880db3fed2ac05e74be12b64be20d8a3fbcfb5c2b' 
  AND token = '03jXeKHuwHJZAmYV5bFNtxtPjmyuVvqRagWF22b6CNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}