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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0d348886533e3de61917fc5dc4e94a8b8ad332033f478e05738a533d61eb346' 
  AND token = 'YPz6fLRfmHoIxrPAuNeVASCm++VmTv4viBggmwII2U8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}