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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6461b1c39a05c0fbd1ca8c0247c3272b44da651b59f27b354e05bbf47dc5f3d1' 
  AND token = 'faJqCoz9bGjGzRSQo2in8IOc/PRmcLH4q5rR3qNdN/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}