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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0784cdb1e440675e8cb5b473d84a150a974744435ee4f036c31b7331cb1e529c' 
  AND token = 'EEFKzhhol65xNmt1hAT8RBIkAhwZ7CXap9J2uFUZkkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}