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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c109bb8dae6e125dfb2bd3d7c2adacb1c9e6181e613747677f8e80698bc1e274' 
  AND token = 'b4gIZyyhzGxA0a8BOvK4pjUVfuySejVZgfrpt4SOUKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}