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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9279fa1c846ed0d181db547b99d7ae09784c6fc9914449b10a171181ed78366' 
  AND token = 'DMFA3GjhCp2KN1MeFnQ6TPuSC5i3IMDaUKilyd9dpDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}