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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4335ce27a0c54987316985c05e8c87030c842d5d6158e9fe9fda86ec278378ef' 
  AND token = '+d09nddtUT09s02cCGmKdc2UXdv8SE2BVMAIN4QVDDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}