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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c66b2df012280cb3d30a080172d4ee5a94f3d1d88d4a1e4fd39b6d31b0710a4' 
  AND token = 'aGuZ1Z230jxxslDQUDWINEsuoIJpjev0JuVyOu32sCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}