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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cabf161e4a9af6e1be9a9787e749e4a5b9b1e4e2b2ca311f493d3b714c012263' 
  AND token = 'KpgrOkMxKUjy+DTiap5V+3lpx9G4uR5gNWFcHqg34PM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}