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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a66804a45adb69ea055d0cc069d13c600230aa13c0b450903f79f8ef47ef558' 
  AND token = '0hJz6apV+6iEvQIiDgGUH2b0wX8MdsqnVH1OYiNwUPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}