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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0dd027e7f9d29a7526d5807a63c26c861ba7383be06d95d4e65cbe24683dd59' 
  AND token = 'TYgacq3ixtV6OfPwzEgpRyzrvoOe5IPhSUyDtgGT1vQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}