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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e62fad2ee364edcffe5145d5dbbc8b45e185699da1f618d2f8a87028292760e2' 
  AND token = 'fxV835xRTGVQ103aOLjO43I67/CZ6wOzD3RxJ6bib7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}