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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b3d242a12bac8cb2016662349a562c06f47db95decb6ec8fac9551b985988d3' 
  AND token = 'HQr4k7fpILCz8aZQxRwzOyZH8RdKVV0uyMpDJt1nlnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}