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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a9c33314073042813d4083b0f048fd6c82b14dca75ded2f994107111c5e2851' 
  AND token = '6Ghx/0+ct2/73TS84bxOHdRvRlZOT4+AxwBT1+piPmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}