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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '442344e362cc5ece9a388606f455a5c41e259f0b0789161416f0764096feeac3' 
  AND token = 'PEsph2pr23aHs5ubWih2Ww+si4FJLMJRpfaslqQJD9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}