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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ede8f8aac93274924531e2e4a91c880f92954cea00347e18363f48b57dd14a9' 
  AND token = 'VmgjxuH5QlYf2qAROVYBLn7oed/wpIUP8E7BpR97QG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}