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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6835ebeafca2fe219c135d87c001cb2bca57be6e64149ee50ef4bc6d300f2bc' 
  AND token = '+bKFt3aM1n4MRr9F03HDI2tEvJFDuLAazZOj+nyXmJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}