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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bdeb756dc70ddc929f00d0807c8b24e9f57586100b2c4be69dbb2167f4d0bb3' 
  AND token = 'TztiZf2bFqIbDDoRRBTj7K+8RP8aC9NbLN4j7hNMLSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}