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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86c8052644b0686cc1baef0858bab468432496e45614dac662b62717ddbd1c4a' 
  AND token = 'G0X6z4UhcgBRh+TB+eejgdcNLdTmvfri60lrSnfRXyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}