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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f449030da5e0cddc35768d4ad1fa5c44a14cbb8ebb5e2ad842de39f1f364a805' 
  AND token = 'Rl5HlUk2QD2Tj35RDbO/WAC5Q0IA4dbNOrUts6NBq7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}