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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6574abec5d37c6a9cc0d676839ad677f6333a2d79db3a4e22411a984aa73f543' 
  AND token = 'HFSnRLoTKf5/woPv0k0bNIAZ6f1Es8qh28LVAKyCmMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}