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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7294997896da20afc3e209920379b0b58628a32f1f990e4b81e99ced7124f00' 
  AND token = 'nkugy1U0QV4yXMzPEwcJA+QCzZBFR7TazBdsMq1fy/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}