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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51e8fcd1f954e6e78e03841717bbafeb7047edb6def97b871c6d616b63887f15' 
  AND token = 'MjggbxySYWvaxJUhDl2DJAAIIbAlPqT5Uyaw2lBB9g4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}