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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59f0effdb6e1a763a4189ee1200270acfc814bf2bdc47a0cf501ac53839e9280' 
  AND token = 'W8KFq4sdCAdp91tBSqymb9/YNaeimmwGViLra7bGyDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}