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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8d4a01c4a8ca3eb5ea4df35513772097c90fa6f425a320458c6b786d596395c' 
  AND token = 'CY8RNidltnbne3+91pTiEs19VgA2WPPn0jew69nhLfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}