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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5e3e05a7d7f16084709aa84b20208b557981d2a1db79fcc595740fe01fb062d' 
  AND token = 'XD0P3PWiVVevce48ARycagfiJe1zK3HQOGNOgOv5Mhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}