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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00d1e2d0d01366c46850da4538f8dc4592956ee3626164a30d1a7bbf2a8e020b' 
  AND token = 'MYzKMQ9j32oM0id+A0jBpZtAdeHEs9mNbLFZqP32yMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}