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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5cf659dde24ef4dbbf76af6a85c8ba03aa807da949a4578b7448e38f967e1fd' 
  AND token = 'e623Hu1YybtTcDoF8BZr8UD2xcLR9dqKQ0XcOyR2LnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}