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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfdd0426721966107147ccf2845787b899458c482e8e5f22a331ce17cb53c3c4' 
  AND token = '0L4s1c8+6TeZSo4s3+A9Tq282TDUXwZbRnsCogZ9yB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}