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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a650f50f4ce03574ac23d37d13a4503e7e3a1cb9420eca5bcdcae17c23fbf215' 
  AND token = 'MM8ShPqY8DdQOAGq0DixuJdEWtzdCy7vF439m4/LphA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}