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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5181363ce87e9f4702f087deadf1d7993d53cd6c697d81e41998a77125fd4cd2' 
  AND token = '371GT4CDlGZzd6AS0+citkkrDvOTHGFQ+s6orPZXMdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}