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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d0224b903c66be2d913e228085db62b2212bd3beb4f5fd678461b6dc1d1e726' 
  AND token = 'XPHbxDPDnc1ziueLt7wDyW3DQUPdSmcfS6TqIZLfd6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}