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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c7f69457a650d2a427cdf21a65bd2fef880fd8191c9fbbd55561aa99e4ddf4' 
  AND token = 'OX8uWcrempWs2bbSaC16nbFdbU75SwAC3pR3j6oX/GI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}