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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09307a2b3d70d03bff49673b52bc19d49e1201e5a0e5e7d9595f3d0032398917' 
  AND token = 'KPS7D1B7DK6nMaeD3OD/GBTDVYmyRgRs8ZRqRqS9Mo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}