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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '444ec8fdd20a718844fc5f41ec370e38e112b1c8f7b6eac4a4c448c66c4e3e8a' 
  AND token = 'MNX+uLTe0kXmGGXH0ca8XN5BQPbKK8JP8T37e4ZqGy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}