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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9ec76825e19aed4fe00723ba3a3522e041f89e6c0f86ca526da9a2d44f899a9' 
  AND token = 'xGVmmUBqEuNuUUdp564o2i2TvlJ+/CtTTz6AMLRyIR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}