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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b12908b29906ac868669f624ca68281d626a92400e74925844c81bd2248ad0d7' 
  AND token = 'wdUMC/CmKlWIPDW/dymWxJqt4zRMiKQ682+F3WoUh8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}