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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ed389f15aebc3ccbf0857e5115b6bcadc03508871bef93f2997b2b9fc07855d' 
  AND token = 'HSy8Zh2DFcryoA7H2SzgpfLp+Ngy0cKQ6W9goPU4TW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}