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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8be8fe1040173755c47b2d43cfc1b762a9b0c67a5e0dcab8f13452064d0c6f02' 
  AND token = 'hz5qUO5rODdl042/fPLrLgRWE98u+cD65eNyJ+c39yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}