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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ab0d620bbe7de79a98dedd62b1ca6b0a14166692d487a7c109bca427b558c49' 
  AND token = 'imki3k5+q6zzyCt06qRBdMNwnGfAQxC/it7kut6Ca0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}