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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d919edf8c8c2b7dc733ce98517a80f87d9c04aa9d22bbed9d66eb3493facde5' 
  AND token = 'DX+Lv+IyyXEJS6M2VPUbhSKMV7YA1rMt40stecKw0mM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}