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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ca5234fa89a2faa65944b72ba17fc05fac5cfde6bd7f98c8a0d6b465cbc2f9' 
  AND token = 'FbEc9GMjEXFk8qmXq5YlOPlMI6YXOg6FbJDyBAWCg/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}