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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42f962df32823e551b9f61d74eb14f04791ac49f2caae3d937cdde86704e2a51' 
  AND token = 'seVVu8hDmuon3Ef2+IYAOGuWubbAKGAYsaj/WjYkANk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}