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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46492e9889754a428108a389370e1802d27d9686a2cf8ab050741ca8bbfd7405' 
  AND token = 'e8qfHif6HiYEvgWbsAYzNwtyJV4EZRIk8HhZ0+lOCEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}