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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66047322fd6b7adb9aa6cdaf6de433f15ed9a6483e212038e649cc88782e9c5c' 
  AND token = 'KXVEPjTpZ5TuXY5031EHkyduXFWIl2oBqTF9VtN9X/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}