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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '990585ed223ffe7e0250a870a53d810fef63d4a084b959c7af24a8ebd268e942' 
  AND token = 'k/+nNQKDU+47UzbSFRGUvwRUXT19hQ7EY5NrSVyaML4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}