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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcd9d178a487b89b1486ef7a5d01ea6c5970d8b872e92639679393ede54dd372' 
  AND token = 'ZKN5WGCxL8T1GRi00+w5ZbXzcRqacmt/8D6B/IE2xRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}