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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c04d2d766b571a73db9106034d47af736214866b3c5f51d0bcfe227bc9e4a08' 
  AND token = '/CisDuUttFkqC7HOyI1AbrCxWimkhOjzsEdf5hMFzTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}